Novirax cream is indicated for the treatment of recurrent herpes labialis (cold sores) in immunocompetent adults and adolescents 12 years of age and older.
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1. Herpes Zoster (Shingles):
2. Genital Herpes Infection:
3. Herpes Labialis:
4. Chickenpox:
Limit alcohol intake while using Acyclovir to prevent any adverse effects.
Acyclovir is a pregnancy Category B medicine. It is not known whether Acyclovir will affect pregnant women or the fetus. Hence, the intake of Acyclovir should be only if prescribed and under medical supervision.
Acyclovir is a pregnancy Category B medicine. It is not known whether Acyclovir will pass through the milk in breastfeeding women. Hence, Acyclovir should only be taken if prescribed by a doctor and under medical supervision.
No interaction found/established
Acyclovir should be taken with caution, especially if you have a history of kidney diseases or conditions. The dose may have to be adjusted by your doctor.
Acyclovir is safe if prescribed by a doctor. It is known not to interact with liver functioning.
Acyclovir works by inhibiting the multiplication of the virus and thereby reducing the severity of the infection.
Common adverse reactions at the application site include dry lips, desquamation, dryness of skin, cracked lips, burning skin, pruritus, flakiness of skin, and stinging. These occurred in less than 1% of patients. Discontinuation due to adverse events occurred in three patients on Novirax cream and one patient on placebo.
Novirax cream is a topical antiviral medication designed to treat recurrent herpes labialis. With a well-established pharmacological profile, it provides targeted relief by inhibiting viral DNA replication. Suitable for use in both adults and adolescents over 12 years of age, it should be applied five times daily for optimal results. The product is safe with minimal side effects and no significant drug interactions.
Acyclovir, the active ingredient in Novirax cream, is an antiviral drug effective against herpes simplex virus (HSV). It is a synthetic purine nucleoside analog with inhibitory activity against HSV types 1 (HSV-1) and 2 (HSV-2). Acyclovir's action is highly selective due to its affinity for the HSV-encoded enzyme thymidine kinase (TK), which converts acyclovir into acyclovir monophosphate, then to diphosphate by cellular guanylate kinase, and finally to triphosphate by various cellular enzymes. Acyclovir triphosphate inhibits herpes viral DNA replication through:
1. Drug-Drug Interaction:
2. Drug-Food Interaction:
3. Drug-Disease Interaction:
Novirax cream is contraindicated in patients with known hypersensitivity to acyclovir, valacyclovir, or any component of the formulation.
Store Novirax cream at room temperature between 20°C to 25°C.
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